Mourinho is frustrated by Manchester United’s progress in the transfer market this summer and his foul mood has increased with poor results during pre-season in America.
He is currently without 17 players having only signed three – Fred, Diogo Dalot and Lee Grant – due to injuries and extended post-World Cup holidays.
And the Portuguese has now been slashed to 7/1 with Ladbrokes to be the next boss out, after only Javi Gracia at trigger-happy Watford, having been 20/1 last week.
Mourinho is now 3/1 to leave Man United before Christmas, and 6/5 to be gone before the end of the season.
Alex Apati of Ladbrokes said: “Mourinho’s odds of leaving have taken another huge hit; not ideal for a man already under pressure in his third season with one of the biggest clubs in the country.”
He added: “A bad start could spark the end of his time in Manchester.”
Mourinho’s mood has seen him launch verbal bullets in the direction of some of his players, his transfer team, and Ed Woodward.
Mourinho wants another two players with a centre-back and a winger his priority, although he started the season also keen on a left-back before opting to stick with Luke Shaw and Ashley Young.
Harry Maguire has overtaken Toby Alderweireld as his top defensive target although images of the Belgian in a United shirt emerged on social media today.
Ivan Perisic is believed to be the top winger target although pictures of Willian also emerged in a United shirt.
United were beaten 4-1 by Liverpool this weekend as Mourinho prepares to tackle Manchester City in a bid to win the title this season.
And Mourinho’s mood is foul.
“This is not our team, not our squad,” he said when explaining the performance.
“We started the game with almost half of the players not going to belong to our squad. So this is not our squad.
“If you say reinforcements, you’re saying players I’d like to buy, to add to the squad, then that’s another thing. But this is not even 30 per cent of my squad, so don’t look to this that way.
“In relation to this game, we have four or five players who are dead, because they care for the club, for the team.
“They tried to give everything, even risking themselves because they don’t want to let all the kids do it by themselves.
“We’re trying to play these matches as best we can. But we can’t do it. What did this game give me? Nothing at all.
“We’re not playing here to improve the team or the dynamic, we’re playing here to just survive and have some not very ugly results.”
On the transfers Mourinho said: “I would like to have two more players, but I think I’m not going to have two.
“I think it’s possible I’m going to have one.
“I gave a list to my club of five names a few months ago and I’ll wait to see if it’s possible to have one of these players.
“If it’s possible it’s possible, if not, it’s not. If it’s not possible, we keep fighting and working and believing in the players that we have.”